ea0037ep188 | Reproduction, endocrine disruptors and signalling | ECE2015
Macejova Dana
, Ondkova Slavomira
, Liska Jan
, Brtko Julius
Introduction: Thyroidal status can play important role in progression mammary gland tumour growth. We have already shown that hypothyroidism induced by application of 6-n-propylthiouracil (PTU) inhibitor of type I iodothyronine 5′-deiodinase (5′-DI) prolonged tumour latency and reduced number, volume and burden of 1-methyl-1-nitrosourea (MNU) induced rat mammary gland tumours in SpragueDawley female rats.1<p class="abstex...